Oral ranitidine hydrochloride is a histamine H2 receptor blocker used to treat certain types of ulcers and other conditions in which your stomach is producing too much acid.

It works by blocking histamine from binding to H2 receptors which then inhibits gastric acid secretion.

FDA Approved Uses

• Used to treat and prevent duodenal ulcers.
• Used to treat gastric ulcers.
• Used to manage gastric hypersecretory states and gastroesophageal reflux disease(GERD).
• Used to treat the symptoms of heartburn.

Contraindications

Inform your doctor before starting therapy and if you are allergic to Ranitidine

Dosage and Administration

Dosages may require modification to adjust for individual sensitivities and associated medical conditions.

Adults Under 60

For short-term treatment of gastric or duodenal active ulceration: 150 mg twice per day or 300 mg at bedtime.

To prevent recurrent gastric or duodenal ulcer: 150 mg taken at bedtime.

For gastroesophageal reflux Disease: 150 mg twice a day.

For erosive esophagitis: 150 mg four times a day. The usual maintenance dose is 150 mg twice a day.

For gastric hypersecretory conditions: 150 mg tablet taken twice per day.

For treatment of heartburn, acid indigestion, and sour stomach: 75 mg at onset of symptoms.

May repeat the dose once in 24 hours.

For prevention of heartburn, acid indigestion, and sour stomach: 75 mg taken 30 to 60 minutes before consuming food or drink expected to cause these symptoms.

Adults 60 and Over

Follow the adult dosage, unless a reduced regimen is recommended by your physician.

Infants and Children

Safety and efficacy have not been established in this age group.

Maximum Dosage Recommendations

Adults: 6 grams per day.

If You Miss a Dose

Take as soon as possible. If close to the next dose, skip and take the next dose. Do not double the dose.

Warning

Indigestion may be a sign of a more serious problem, for example heart problems. Watch for these warning signs and contact your doctor if:

• Your indigestion is not helped by any lifestyle changes recommended by your doctor.
• You are 40 years of age or older and have previously had good digestion.
• Your bowel motions are dark, black and look like tar.
• Your vomit appears to contain blood or look like ground coffee.
• You have recently lost weigh and/or generally feel unwell.
• You have pain or difficulty swallowing food.
• Your chest pain or burning is not helped with indigestion medicines.